PADI6 Back

peptidyl arginine deiminase, type VI

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NCBI Description of PADI6

This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. This protein may play a role in cytoskeletal reorganization in the egg and in early embryo development.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


PADI6 is highly significantly mutated in
PADI6 is significantly mutated in
PADI6 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for PADI6