PAAF1 Back

proteasomal ATPase-associated factor 1

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NCBI Description of PAAF1

This gene encodes a WD repeat-containing protein involved in regulation of association of proteasome components. During HIV infection, the encoded protein is thought to promote provirus transcription through recruitment of the 19S regulatory complex. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Community Annotation of PAAF1 Add / Edit PAAF1: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


PAAF1 is highly significantly mutated in
PAAF1 is significantly mutated in
PAAF1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for PAAF1