P2RY12 Back

purinergic receptor P2Y, G-protein coupled, 12

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of P2RY12

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelets aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Two transcript variants encoding the same isoform have been identified for this gene.

Community Annotation of P2RY12 Add / Edit P2RY12: Annotations

No community annotations yet for P2RY12.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

P2RY12 is highly significantly mutated in
(none)
P2RY12 is significantly mutated in
(none)
P2RY12 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for P2RY12