P2RX2 Back

purinergic receptor P2X, ligand-gated ion channel, 2

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NCBI Description of P2RX2
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Six transcript variants encoding six distinct isoforms have been identified for this gene.

Community Annotation of P2RX2 Add / Edit P2RX2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

P2RX2 is highly significantly mutated in
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P2RX2 is significantly mutated in
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P2RX2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for P2RX2