OVGP1 Back

oviductal glycoprotein 1, 120kDa (mucin 9, oviductin)

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NCBI Description of OVGP1

This gene encodes a large, carbohydrate-rich, epithelial glycoprotein with numerous O-glycosylation sites located within threonine, serine, and proline-rich tandem repeats. The gene is similar to members of the mucin and the glycosyl hydrolase 18 gene families. Regulation of expression may be estrogen-dependent. Gene expression and protein secretion occur during late follicular development through early cleavage-stage embryonic development. The protein is secreted from non-ciliated oviductal epithelial cells and associates with ovulated oocytes, blastomeres, and spermatozoan acrosomal regions.

Community Annotation of OVGP1 Add / Edit OVGP1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

OVGP1 is highly significantly mutated in
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OVGP1 is significantly mutated in
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OVGP1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for OVGP1