OTOS Back

otospiralin

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NCBI Description of OTOS
Otospiralin is synthesized by nonsensory cells (fibrocytes) of the inner ear, and downregulation of otospiralin in guinea pigs leads to deafness (Lavigne-Rebillard et al., 2003 [PubMed 12687421]).[supplied by OMIM, Mar 2008].

Community Annotation of OTOS Add / Edit OTOS: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

OTOS is highly significantly mutated in
(none)
OTOS is significantly mutated in
(none)
OTOS is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for OTOS