OSM Back

oncostatin M

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of OSM
Oncostatin M is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. This gene encodes a growth regulator which inhibits the proliferation of a number of tumor cell lines. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells.

Community Annotation of OSM Add / Edit OSM: Annotations

No community annotations yet for OSM.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

OSM is highly significantly mutated in
(none)
OSM is significantly mutated in
(none)
OSM is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for OSM