OSBPL8 Back

oxysterol binding protein-like 8

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NCBI Description of OSBPL8
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Two transcript variants encoding different isoforms have been found for this gene.

Community Annotation of OSBPL8 Add / Edit OSBPL8: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

OSBPL8 is highly significantly mutated in
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OSBPL8 is significantly mutated in
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OSBPL8 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for OSBPL8