oxysterol binding protein

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NCBI Description of OSBP

Oxysterol binding protein is an intracellular protein that is believed to transport sterols from lysosomes to the nucleus where the sterol down-regulates the genes for the LDL receptor, HMG-CoA reductase, and HMG synthetase Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

Community Annotation of OSBP Add / Edit OSBP: Annotations

No community annotations yet for OSBP.
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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


OSBP is highly significantly mutated in
OSBP is significantly mutated in
OSBP is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for OSBP