OAS3 Back

2'-5'-oligoadenylate synthetase 3, 100kDa

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NCBI Description of OAS3
This gene encodes an enzyme included in the 2', 5' oligoadenylate synthase family. This enzyme is induced by interferons and catalyzes the 2', 5' oligomers of adenosine in order to bind and activate RNase L. This enzyme family plays a significant role in the inhibition of cellular protein synthesis and viral infection resistance.

Community Annotation of OAS3 Add / Edit OAS3: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

OAS3 is highly significantly mutated in
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OAS3 is significantly mutated in
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OAS3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for OAS3