NXF5 Back

nuclear RNA export factor 5

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NCBI Description of NXF5
This gene is one member of a family of nuclear RNA export factor genes. The encoded protein can bind RNA, and is implicated in mRNA nuclear export. However, this protein has lost several C-terminal protein domains found in other family members that are required for export activity, and may be an evolving pseudogene. Alternatively spliced transcript variants have been described, but most are candidates for nonsense-mediated decay (NMD) and may not express proteins in vivo.

Community Annotation of NXF5 Add / Edit NXF5: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NXF5 is highly significantly mutated in
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NXF5 is significantly mutated in
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NXF5 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for NXF5