NVL Back

nuclear VCP-like

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of NVL
This gene encodes a member of the AAA (ATPases associated with diverse cellular activities) superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. Two encoded proteins, described as major and minor isoforms, have been localized to distinct regions of the nucleus. The largest encoded protein (major isoform) has been localized to the nucleolus and shown to participate in ribosome biosynthesis (PMID: 15469983, 16782053), while the minor isoform has been localized to the nucleoplasmin.

Community Annotation of NVL Add / Edit NVL: Annotations

No community annotations yet for NVL.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NVL is highly significantly mutated in
(none)
NVL is significantly mutated in
(none)
NVL is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for NVL