NVL Back

nuclear VCP-like

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NCBI Description of NVL

This gene encodes a member of the AAA (ATPases associated with diverse cellular activities) superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. Two encoded proteins, described as major and minor isoforms, have been localized to distinct regions of the nucleus. The largest encoded protein (major isoform) has been localized to the nucleolus and shown to participate in ribosome biosynthesis (PMID: 15469983, 16782053), while the minor isoform has been localized to the nucleoplasmin.

Community Annotation of NVL Add / Edit NVL: Annotations

No community annotations yet for NVL.
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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


NVL is highly significantly mutated in
NVL is significantly mutated in
NVL is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for NVL