NUPL1 Back

nucleoporin like 1

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NCBI Description of NUPL1
This gene encodes a member of the nucleoporin family that shares 87% sequence identity with rat nucleoporin p58. The protein is localized to the nuclear rim and is a component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Community Annotation of NUPL1 Add / Edit NUPL1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NUPL1 is highly significantly mutated in
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NUPL1 is significantly mutated in
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NUPL1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for NUPL1