NUDT9 Back

nudix (nucleoside diphosphate linked moiety X)-type motif 9

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of NUDT9

The protein encoded by this gene belongs to the Nudix hydrolase family. Nudix boxes are found in a family of diverse enzymes that catalyze the hydrolysis of nucleoside diphosphate derivatives. This enzyme is an ADP-ribose pyrophosphatase that catalyzes the hydrolysis of ADP-ribose to AMP and ribose-5-P. It requires divalent metal ions and an intact Nudix motif for enzymatic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Community Annotation of NUDT9 Add / Edit NUDT9: Annotations

No community annotations yet for NUDT9.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NUDT9 is highly significantly mutated in
(none)
NUDT9 is significantly mutated in
(none)
NUDT9 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for NUDT9