NUDT18 Back

nudix (nucleoside diphosphate linked moiety X)-type motif 18

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NCBI Description of NUDT18

The protein encoded by this gene is a member of the Nudix hydrolase family. Nudix hydrolases eliminate potentially toxic nucleotide metabolites from the cell and regulate the concentrations and availability of many different nucleotide substrates, cofactors, and signaling molecules. This protein contains a Nudix hydrolase domain and hydrolyzes oxidized forms of guanosine and deoxyguanosine diphosphates.

Community Annotation of NUDT18 Add / Edit NUDT18: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NUDT18 is highly significantly mutated in
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NUDT18 is significantly mutated in
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NUDT18 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for NUDT18