NSA2 Back

NSA2 ribosome biogenesis homolog (S. cerevisiae)

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NCBI Description of NSA2

This gene encodes a nucleolar protein involved in cell cycle regulation and proliferation. This gene was identified based on sequence similarity to a highly conserved Saccharomyces cerevisiae gene encoding a pre-ribosomal protein, which is involved in large ribosomal subunit biogenesis. The encoded protein is found at elevated levels in diabetic nephropathy. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


NSA2 is highly significantly mutated in
NSA2 is significantly mutated in
NSA2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for NSA2