NRL Back

neural retina leucine zipper

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NCBI Description of NRL
This gene encodes a basic motif-leucine zipper transcription factor of the Maf subfamily. The encoded protein is conserved among vertebrates and is a critical intrinsic regulator of photoceptor development and function. Mutations in this gene have been associated with retinitis pigmentosa and retinal degenerative diseases.

Community Annotation of NRL Add / Edit NRL: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NRL is highly significantly mutated in
(none)
NRL is significantly mutated in
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NRL is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for NRL