NR1D2 Back

nuclear receptor subfamily 1, group D, member 2

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NCBI Description of NR1D2

This gene encodes a member of the nuclear hormone receptor family, specifically the NR1 subfamily of receptors. The encoded protein functions as a transcriptional repressor and may play a role in circadian rhythms and carbohydrate and lipid metabolism. Alternatively spliced transcript variants have been described.

Community Annotation of NR1D2 Add / Edit NR1D2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NR1D2 is highly significantly mutated in
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NR1D2 is significantly mutated in
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NR1D2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for NR1D2