NPM3 Back

nucleophosmin/nucleoplasmin, 3

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NCBI Description of NPM3
The protein encoded by this gene is related to the nuclear chaperone phosphoproteins, nucleoplasmin and nucleophosmin. This protein is strongly expressed in diverse cell types where it localizes primarily to the nucleus. Based on its similarity to nucleoplasmin and nucleophosmin, this protein likely functions as a molecular chaperone in the cell nucleus.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NPM3 is highly significantly mutated in
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NPM3 is significantly mutated in
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NPM3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for NPM3