neuropeptide FF receptor 2

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NCBI Description of NPFFR2

This gene encodes a member of a subfamily of G-protein-coupled neuropeptide receptors. This protein is activated by the neuropeptides A-18-amide (NPAF) and F-8-amide (NPFF) and may function in pain modulation and regulation of the opioid system. Alternative splicing results in multiple transcript variants.

Community Annotation of NPFFR2 Add / Edit NPFFR2: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


NPFFR2 is highly significantly mutated in
NPFFR2 is significantly mutated in
NPFFR2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for NPFFR2