NPAS2 Back

neuronal PAS domain protein 2

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NCBI Description of NPAS2

The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH)-PAS family of transcription factors. A similar mouse protein may play a regulatory role in the acquisition of specific types of memory. It also may function as a part of a molecular clock operative in the mammalian forebrain.

Community Annotation of NPAS2 Add / Edit NPAS2: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


NPAS2 is highly significantly mutated in
NPAS2 is significantly mutated in
NPAS2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for NPAS2