NOX5 Back

NADPH oxidase, EF-hand calcium binding domain 5

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NCBI Description of NOX5
This gene is predominantly expressed in the testis and lymphocyte-rich areas of spleen and lymph nodes. It encodes a calcium-dependen NADPH oxidase that generates superoxide, and functions as a calcium-dependent proton channel that may regulate redox-dependent processes in lymphocytes and spermatozoa. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Community Annotation of NOX5 Add / Edit NOX5: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NOX5 is highly significantly mutated in
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NOX5 is significantly mutated in
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NOX5 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for NOX5