NOS3 Back

nitric oxide synthase 3 (endothelial cell)

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of NOS3
Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Multiple transcript variants encoding different isoforms have been found for this gene.

Community Annotation of NOS3 Add / Edit NOS3: Annotations

No community annotations yet for NOS3.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NOS3 is highly significantly mutated in
(none)
NOS3 is significantly mutated in
(none)
NOS3 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for NOS3