NONO Back

non-POU domain containing, octamer-binding

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NCBI Description of NONO
This gene encodes an RNA-binding protein which plays various roles in the nucleus, including transcriptional regulation and RNA splicing. A rearrangement between this gene and the transcription factor E3 gene has been observed in papillary renal cell carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes exist on Chromosomes 2 and 16.

Community Annotation of NONO Add / Edit NONO: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NONO is highly significantly mutated in
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NONO is significantly mutated in
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NONO is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for NONO