NOL3 Back

nucleolar protein 3 (apoptosis repressor with CARD domain)

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NCBI Description of NOL3

This gene encodes an anti-apoptotic protein that has been shown to down-regulate the enzyme activities of caspase 2, caspase 8 and tumor protein p53. Multiple transcript variants encoding different isoforms have been found for this gene.

Community Annotation of NOL3 Add / Edit NOL3: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NOL3 is highly significantly mutated in
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NOL3 is significantly mutated in
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NOL3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for NOL3