NCBI Description of NNT
|This gene encodes an integral protein of the inner mitochondrial membrane. The enzyme couples hydride transfer between NAD(H) and NADP(+) to proton translocation across the inner mitochondrial membrane. Under most physiological conditions, the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH. The resulting NADPH is used for biosynthesis and in free radical detoxification. Two alternatively spliced variants, encoding the same protein, have been found for this gene.|
Community Annotation of NNT Add / Edit NNT: Annotations
No community annotations yet for NNT.
• "Mouse over" a mutation to see details.
Click on a tumor type to see its full list of significant genes.