NMT2 Back

N-myristoyltransferase 2

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of NMT2
N-myristoyltransferase (NMT) catalyzes the reaction of N-terminal myristoylation of many signaling proteins. It transfers myristic acid from myristoyl coenzyme A to the amino group of a protein's N-terminal glycine residue. Biochemical evidence indicates the presence of several distinct NMTs, varying in apparent molecular weight and /or subcellular distribution. The predicted 498-amino acid of human NMT2 protein shares 77% and 96% sequence identity with human NMT1 and mouse Nmt2 comprise two distinct families of N-myristoyltransferases.

Community Annotation of NMT2 Add / Edit NMT2: Annotations

No community annotations yet for NMT2.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NMT2 is highly significantly mutated in
(none)
NMT2 is significantly mutated in
(none)
NMT2 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for NMT2