NMI Back

N-myc (and STAT) interactor

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of NMI
NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias.

Community Annotation of NMI Add / Edit NMI: Annotations

No community annotations yet for NMI.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NMI is highly significantly mutated in
(none)
NMI is significantly mutated in
(none)
NMI is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for NMI