NME2 Back

non-metastatic cells 2, protein (NM23B) expressed in

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NCBI Description of NME2
Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by NME1) and 'B' (encoded by this gene) isoforms. Multiple alternatively spliced transcript variants have been found for this gene. Read-through transcription from the neighboring upstream gene (NME1) generates naturally-occurring transcripts (NME1-NME2) that encode a fusion protein comprised of sequence sharing identity with each individual gene product.

Community Annotation of NME2 Add / Edit NME2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NME2 is highly significantly mutated in
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NME2 is significantly mutated in
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NME2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for NME2