NLRC5 Back

NLR family, CARD domain containing 5

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NCBI Description of NLRC5

This gene encodes a member of the caspase recruitment domain-containing NLR family. This gene plays a role in cytokine response and antiviral immunity through its inhibition of NF-kappa-B activation and negative regulation of type I interferon signaling pathways.

Community Annotation of NLRC5 Add / Edit NLRC5: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NLRC5 is highly significantly mutated in
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NLRC5 is significantly mutated in
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NLRC5 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for NLRC5