NLN Back

neurolysin (metallopeptidase M3 family)

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of NLN
This gene encodes a member of the metallopeptidase M3 protein family that cleaves neurotensin at the Pro10-Tyr11 bond, leading to the formation of neurotensin(1-10) and neurotensin(11-13). The encoded protein is likely involved in the termination of the neurotensinergic signal in the central nervous system and in the gastrointestinal tract. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

Community Annotation of NLN Add / Edit NLN: Annotations

No community annotations yet for NLN.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NLN is highly significantly mutated in
(none)
NLN is significantly mutated in
(none)
NLN is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for NLN