NLGN3 Back

neuroligin 3

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NCBI Description of NLGN3

This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. Mutations in this gene may be associated with autism and Asperger syndrome. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Community Annotation of NLGN3 Add / Edit NLGN3: Annotations

No community annotations yet for NLGN3.
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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


NLGN3 is highly significantly mutated in
NLGN3 is significantly mutated in
NLGN3 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for NLGN3