NKX3-1 Back

NK3 homeobox 1

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of NKX3-1
This gene encodes a homeobox-containing transcription factor. This transcription factor functions as a negative regulator of epithelial cell growth in prostate tissue. Aberrant expression of this gene is associated with prostate tumor progression. Alternate splicing results in multiple transcript variants of this gene.

Community Annotation of NKX3-1 Add / Edit NKX3-1: Annotations

No community annotations yet for NKX3-1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NKX3-1 is highly significantly mutated in
(none)
NKX3-1 is significantly mutated in
(none)
NKX3-1 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for NKX3-1