NKX2-3 Back

NK2 transcription factor related, locus 3 (Drosophila)

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NCBI Description of NKX2-3
This gene encodes a homeodomain-containing transcription factor. The encoded protein is a member of the NKX family of homeodomain transcription factors. Studies of similar proteins in mouse and rat have indicated a potential role in cellular differentiation. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by orthologous data and transcript alignments.

Community Annotation of NKX2-3 Add / Edit NKX2-3: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NKX2-3 is highly significantly mutated in
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NKX2-3 is significantly mutated in
(none)
NKX2-3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for NKX2-3