NKRF Back

NFKB repressing factor

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NCBI Description of NKRF
This gene encodes a transcriptional repressor that interacts with specific negative regulatory elements to mediate transcriptional repression of certain nuclear factor kappa B responsive genes. The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm. Alternate splicing results in multiple transcript variants.

Community Annotation of NKRF Add / Edit NKRF: Annotations

No community annotations yet for NKRF.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NKRF is highly significantly mutated in
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NKRF is significantly mutated in
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NKRF is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for NKRF