NIT1 Back

nitrilase 1

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NCBI Description of NIT1

This gene encodes a member of the nitrilase protein family with homology to bacterial and plant nitrilases, enzymes that cleave nitriles and organic amides to the corresponding carboxylic acids plus ammonia. Multiple transcript variants encoding different isoforms have been found for this gene.

Community Annotation of NIT1 Add / Edit NIT1: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


NIT1 is highly significantly mutated in
NIT1 is significantly mutated in
NIT1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for NIT1