NIN Back

ninein (GSK3B interacting protein)

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NCBI Description of NIN
This gene encodes one of the proteins important for centrosomal function. This protein is important for positioning and anchoring the microtubules minus-ends in epithelial cells. Localization of this protein to the centrosome requires three leucine zippers in the central coiled-coil domain. Multiple alternatively spliced transcript variants that encode different isoforms have been reported.

Community Annotation of NIN Add / Edit NIN: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NIN is highly significantly mutated in
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NIN is significantly mutated in
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NIN is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for NIN