NHP2L1 Back

NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)

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NCBI Description of NHP2L1
Originally named because of its sequence similarity to the Saccharomyces cerevisiae NHP2 (non-histone protein 2), this protein appears to be a highly conserved nuclear protein that is a component of the [U4/U6.U5] tri-snRNP. It binds to the 5' stem-loop of U4 snRNA. Two transcript variants encoding the same protein have been found for this gene.

Community Annotation of NHP2L1 Add / Edit NHP2L1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NHP2L1 is highly significantly mutated in
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NHP2L1 is significantly mutated in
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NHP2L1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for NHP2L1