NFKBIE Back

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of NFKBIE
The protein encoded by this gene binds to components of NF-kappa-B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF-kappa-B by making it available to translocate to the nucleus.

Community Annotation of NFKBIE Add / Edit NFKBIE: Annotations

No community annotations yet for NFKBIE.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NFKBIE is highly significantly mutated in
(none)
NFKBIE is significantly mutated in
(none)
NFKBIE is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for NFKBIE