NFIX Back

nuclear factor I/X (CCAAT-binding transcription factor)

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NCBI Description of NFIX
The protein encoded by this gene is a transcription factor that binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3 in viral and cellular promoters. The encoded protein can also stimulate adenovirus replication in vitro. Three transcript variants encoding different isoforms have been found for this gene.

Community Annotation of NFIX Add / Edit NFIX: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NFIX is highly significantly mutated in
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NFIX is significantly mutated in
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NFIX is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for NFIX