NFIC Back

nuclear factor I/C (CCAAT-binding transcription factor)

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NCBI Description of NFIC

The protein encoded by this gene belongs to the CTF/NF-I family. These are dimeric DNA-binding proteins, and function as cellular transcription factors and as replication factors for adenovirus DNA replication. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Community Annotation of NFIC Add / Edit NFIC: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NFIC is highly significantly mutated in
(none)
NFIC is significantly mutated in
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NFIC is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for NFIC