NFAM1 Back

NFAT activating protein with ITAM motif 1

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NCBI Description of NFAM1
The protein encoded by this gene is a type I membrane receptor that activates cytokine gene promoters such as the IL-13 and TNF-alpha promoters. The encoded protein contains an immunoreceptor tyrosine-based activation motif (ITAM) and is thought to regulate the signaling and development of B-cells.

Community Annotation of NFAM1 Add / Edit NFAM1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NFAM1 is highly significantly mutated in
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NFAM1 is significantly mutated in
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NFAM1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for NFAM1