NEUROG3 Back

neurogenin 3

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NCBI Description of NEUROG3

The protein encoded by this gene is a basic helix-loop-helix (bHLH) transcription factor involved in neurogenesis. The encoded protein likely acts as a heterodimer with another bHLH protein. Defects in this gene are a cause of congenital malabsorptive diarrhea 4 (DIAR4).

Community Annotation of NEUROG3 Add / Edit NEUROG3: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NEUROG3 is highly significantly mutated in
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NEUROG3 is significantly mutated in
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NEUROG3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for NEUROG3