NEUROD2 Back

neurogenic differentiation 2

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NCBI Description of NEUROD2
This gene encodes a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. Expression of this gene can induce transcription from neuron-specific promoters, such as the GAP-43 promoter, which contain a specific DNA sequence known as an E-box. The product of the human gene can induce neurogenic differentiation in non-neuronal cells in Xenopus embryos, and is thought to play a role in the determination and maintenance of neuronal cell fates.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NEUROD2 is highly significantly mutated in
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NEUROD2 is significantly mutated in
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NEUROD2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for NEUROD2