NEU3 Back

sialidase 3 (membrane sialidase)

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NCBI Description of NEU3

This gene product belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids. It is localized in the plasma membrane, and its activity is specific for gangliosides. It may play a role in modulating the ganglioside content of the lipid bilayer.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


NEU3 is highly significantly mutated in
NEU3 is significantly mutated in
NEU3 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for NEU3