NCBI Description of NET1
|This gene is part of the family of Rho guanine nucleotide exchange factors. Members of this family activate Rho proteins by catalyzing the exchange of GDP for GTP. The protein encoded by this gene interacts with RhoA within the cell nucleus and may play a role in repairing DNA damage after ionizing radiation. Pseudogenes of this gene are located on the long arms of chromosomes 1, 7 and 18. Alternative splicing results in multiple transcript variants that encode different protein isoforms.|
Community Annotation of NET1 Add / Edit NET1: Annotations
No community annotations yet for NET1.
• "Mouse over" a mutation to see details.
Click on a tumor type to see its full list of significant genes.