NEK11 Back

NIMA (never in mitosis gene a)- related kinase 11

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NCBI Description of NEK11

This gene encodes a member of the never in mitosis gene A family of kinases. The encoded protein localizes to the nucleoli, and may function with NEK2A in the S-phase checkpoint. The encoded protein appears to play roles in DNA replication and response to genotoxic stress. Alternatively spliced transcript variants have been described.

Community Annotation of NEK11 Add / Edit NEK11: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NEK11 is highly significantly mutated in
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NEK11 is significantly mutated in
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NEK11 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for NEK11