NEIL3 Back

nei endonuclease VIII-like 3 (E. coli)

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NCBI Description of NEIL3
NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).[supplied by OMIM, Mar 2008].

Community Annotation of NEIL3 Add / Edit NEIL3: Annotations

No community annotations yet for NEIL3.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NEIL3 is highly significantly mutated in
(none)
NEIL3 is significantly mutated in
(none)
NEIL3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for NEIL3