NEIL1 Back

nei endonuclease VIII-like 1 (E. coli)

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NCBI Description of NEIL1

This gene is a member of the Nei endonuclease VIII-like gene family which encodes DNA glycosylases. The encoded enzyme participates in the DNA repair pathway by initiating base excision repair by removing damaged bases, primarily oxidized pyrimidines. Multiple transcript variants encoding different isoforms have been found for this gene.

Community Annotation of NEIL1 Add / Edit NEIL1: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


NEIL1 is highly significantly mutated in
NEIL1 is significantly mutated in
NEIL1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for NEIL1