NEDD9 Back

neural precursor cell expressed, developmentally down-regulated 9

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NCBI Description of NEDD9
The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants.

Community Annotation of NEDD9 Add / Edit NEDD9: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

NEDD9 is highly significantly mutated in
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NEDD9 is significantly mutated in
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NEDD9 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for NEDD9